Epigenetic long read sequencing
Qugen is offering long read epigenetic 5mC sequencing within and outside CpG islands with unprecedented accuracy using our proprietary technology. We can determine the age of your tissues: Angew. Chem. Int. Ed. 2024, 10.1002/anie.202418500
Quantification of epigenetic marks
Qugen is offering exact mass spectrometry based quantification of epigenetic nucleosides in DNA and RNA using out internal isotope standards technology.
Nat. Protoc. 2018, doi: 10.1038/s41596-018-0094-6 and Nature 2016, 537 (7618), 63-68.
Epigenetic TET3 enzyme Webshop
In our Webshop we offer our proprietary high performance TET3 enzymes which allow the selective and efficient oxidation of 5mC to 5caC or alternatively the oxidation of 5mC to 5hmC and 5fC for epigenetic sequencing. These enzyme are fully compatible with all TET based epigenetic sequencing methods including TABS. Angew. Chem. Int. Ed. 2024, 10.1002/anie.202418500. RSC Chem. Biol. 2025, doi: 10.1039/D4CB00315B.
Influencing the Epigenome to cure cancer
All the the technologies were developed in order to find substances that can reset the epigenetic program of cells and organism in order to attack cancer with their misguided epigenome at the epigenetic level. Our first development, compound QE2019-1 shows unprecedented success in treating the diseases AML and MDS in mouse xenograft models.
Our support goes beyond sample preparation and sequencing
if needed, we provide assistance also for downstream data analysis. We're here to help - every step of the way!.
QuGen GmbH
Herbstweg 13
82152 Krailling
Phone: +49 89 86 46 64 83
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